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Structure of 2844-05-5
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2-Bromo-6-(trifluoromethyl)phenol features a strategically positioned trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the bromine substituent enables direct functionalization in cross-coupling reactions. This phenolic scaffold serves as a key building block for bioactive molecules and advanced materials.
2-Bromo-6-(trifluoromethyl)phenol serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its bromine substituent provides high reactivity under standard conditions, while the trifluoromethyl group enhances metabolic stability and lipophilicity. The compound exhibits good bench stability and facilitates efficient functionalization in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: