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Dichloro(N,N,N',N'-tetramethylethylenediamine)zinc

  • CAS No. 28308-00-1

  • Cat. No. CS-0085489
  • Purity≥97%
  • MDL No.MFCD00013233

*For research and further manufacturing use only, not for direct human use.

Dichloro(N,N,N',N'-tetramethylethylenediamine)zinc|CS-0085489

Structure of 28308-00-1

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General Information

  • CAS No. 28308-00-1
  • Cat. No. CS-0085489
  • Purity ≥97%
  • MDL No. MFCD00013233
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆Cl₂N₂Zn
  • Molecular Weight 252.49
  • Synonym(s) ZnCl2-TMEDA
  • SMILES Cl[Zn]1(Cl)[N](C)(C)CC[N]1(C)C

Description

Dichloro(N,N,N',N'-tetramethylethylenediamine)zinc serves as a stable, moisture-tolerant zinc source for catalytic transformations. The tetramethylethylenediamine ligand enhances solubility and reactivity in organic media. This complex facilitates efficient cross-coupling and functionalization reactions under mild conditions.

Application

Dichloro(N,N,N',N'-tetramethylethylenediamine)zinc serves as a stable, bench-friendly zinc source for cross-coupling reactions. It facilitates efficient Negishi-type couplings with aryl and vinyl halides under mild conditions, offering excellent functional group tolerance and ease of handling. The tetramethylethylenediamine ligand enhances solubility and reactivity while minimizing side reactions, making it well-suited for iterative synthesis and scalable applications in medicinal chemistry and materials science.

Synthesis

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    • In-stock
      Dichloro(N,N,N',N'-tetramethylethylenediamine)zinc|CS-0085489
      28308-00-1

    References

    • Adam, Abdel Majid A.; Refat, Moamen S.; Sharshar; Heiba Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2012 , vol. 95, p. 458 - 477

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3263
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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