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CS-W001157 4
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N-Cyclohexyl-1,3-benzothiazol-2-amine

  • CAS No. 28291-75-0

  • Cat. No. CS-0263426
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Cyclohexyl-1,3-benzothiazol-2-amine|CS-0263426

Structure of 28291-75-0

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General Information

  • CAS No. 28291-75-0
  • Cat. No. CS-0263426
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₆N₂S
  • Molecular Weight 232.34
  • Synonym(s) N-Cyclohexylbenzothiazole-2-amine
  • SMILES C1(NC2CCCCC2)=NC3=CC=CC=C3S1

Description

N-Cyclohexyl-1,3-benzothiazol-2-amine features a benzothiazole core with a cyclohexylamino substituent, delivering enhanced solubility and thermal stability. This structure enables robust performance in catalytic systems and polymer synthesis, where electron-rich nitrogen centers facilitate efficient coupling reactions under standard conditions.

Application

N-Cyclohexyl-1,3-benzothiazol-2-amine serves as a robust scaffold for heterocyclic synthesis and functional group manipulation. Its benzothiazole core provides enhanced stability and electron-rich character, enabling efficient coupling reactions and facilitating the construction of complex molecular architectures. The cyclohexyl amine moiety offers favorable solubility and compatibility in organic media, supporting broad utility in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Yao, Ruiya; Liu, Haiyi; Wu, Yichao; Cai, Mingzhong Applied Organometallic Chemistry, 2013 , vol. 27, # 2 p. 109 - 113
  • Route2
    • null|null
      250122-02-2
    • ~%
    • In-stock
      N-Cyclohexyl-1,3-benzothiazol-2-amine|CS-0263426
      28291-75-0

    References

    • Rout, Saroj Kumar; Guin, Srimanta; Nath, Jayashree; Patel, Bhisma K. Green Chemistry, 2012 , vol. 14, # 9 p. 2491 - 2498
  • Route3
    • 1-Cyclohexyl-3-phenylthiourea|CS-0322567
      722-03-2
    • ~99%
    • In-stock
      N-Cyclohexyl-1,3-benzothiazol-2-amine|CS-0263426
      28291-75-0

    References

    • Hoechst Aktiengesellschaft Patent: US4252963 A1, 1981 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   4.0409
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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