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CS-W001157 4
Total: USD 88.00

Potassium trifluoro(4-fluoro-2-methylbenzyl)borate

  • CAS No. 2828444-52-4

  • Cat. No. CS-0626240
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(4-fluoro-2-methylbenzyl)borate|CS-0626240

Structure of 2828444-52-4

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Description

Potassium trifluoro(4-fluoro-2-methylbenzyl)borate delivers a stable, moisture-tolerant boronate moiety bearing a para-fluoro and ortho-methyl substituent on the benzyl ring. This configuration enhances electrophilic reactivity in Suzuki-Miyaura couplings while maintaining bench stability under standard conditions.

Application

Potassium trifluoro(4-fluoro-2-methylbenzyl)borate serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. Its trifluoroborate group enables efficient C–C bond formation under mild conditions, with the 4-fluoro-2-methylphenyl moiety providing orthogonal reactivity and enhanced metabolic stability in biaryl scaffold construction. The compound exhibits excellent functional group tolerance and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.

General Information

  • CAS No. 2828444-52-4
  • Cat. No. CS-0626240
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BF₄K
  • Molecular Weight 230.05
  • Synonym(s) None
  • SMILES CC1=CC(F)=CC=C1C[B-](F)(F)F.[K+]

Computational Chemistry Data

  • TPSA   0
  • LogP   0.06722
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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