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CS-W001157 4
Total: USD 88.00

2-((4-Fluorophenyl)sulfonyl)ethanol

  • CAS No. 28122-13-6

  • Cat. No. CS-0157418
  • Purity≥96%
  • MDL No.MFCD03789137

*For research and further manufacturing use only, not for direct human use.

2-((4-Fluorophenyl)sulfonyl)ethanol|CS-0157418

Structure of 28122-13-6

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General Information

  • CAS No. 28122-13-6
  • Cat. No. CS-0157418
  • Purity ≥96%
  • MDL No. MFCD03789137
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉FO₃S
  • Molecular Weight None
  • Synonym(s) 4-FLUOROPHENYLSULFONYLETHANOL
  • SMILES C1=C(C=CC(=C1)S(=O)(=O)CCO)F

Description

2-((4-Fluorophenyl)sulfonyl)ethanol features a fluorinated phenyl ring linked via a sulfonyl group to a terminal hydroxymethyl moiety. This configuration imparts enhanced solubility and metabolic stability, enabling efficient integration into complex molecular architectures. The molecule serves as a robust scaffold for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

2-((4-Fluorophenyl)sulfonyl)ethanol serves as a versatile sulfonate building block in synthetic organic chemistry, enabling efficient C–O and C–N bond formation via nucleophilic substitution. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward purification and integration into multi-step syntheses, particularly for constructing sulfonamide-containing heterocycles and pharmaceutical intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P405-P501

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Computational Chemistry Data

  • TPSA   54.37
  • LogP   0.5917
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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