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CS-W001157 4
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Ethyl thiophene-2-carboxylate

  • CAS No. 2810-04-0

  • Cat. No. CS-W016234
  • Purity≥97%
  • MDL No.MFCD00005436

*For research and further manufacturing use only, not for direct human use.

Ethyl thiophene-2-carboxylate|CS-W016234

Structure of 2810-04-0

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General Information

  • CAS No. 2810-04-0
  • Cat. No. CS-W016234
  • Purity ≥97%
  • MDL No. MFCD00005436
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈O₂S
  • Molecular Weight 156.20
  • Synonym(s) Ethyl 2-thiophenecarboxylate
  • SMILES O=C(C1=CC=CS1)OCC

Description

It is an important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field.

Application

Ethyl thiophene-2-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized thiophene derivatives. Its ester group facilitates nucleophilic acyl substitution and reduction reactions, while the thiophene core provides inherent stability and electronic properties valuable in pharmaceutical and agrochemical synthesis. The molecule exhibits good bench stability and is compatible with standard reaction conditions, simplifying purification and scale-up.

Synthesis

  • Route1

    References

    • Li, Yan; Chen, Huan-Huan; Wang, Chu-Fei; Xu, Xiao-Lan; Feng, Yi-Si Tetrahedron Letters, 2012 , vol. 53, # 43 p. 5796 - 5799
  • Route2
    • In-stock
      Rivaroxaban impurity 50|CS-W020070
      527-72-0
    • null|null
      64-17-5
    • ~85%
    • In-stock
      Ethyl thiophene-2-carboxylate|CS-W016234
      2810-04-0

    References

    • Liang, Yong-Min; Xu, Qi-Hai; Wu, Xiao-Li; Ma, Yong-Xiang Journal of Chemical Research, 2004 , # 3 p. 226 - 227
  • Route3
    • In-stock
      Rivaroxaban impurity 50|CS-W020070
      527-72-0
    • null|null
      75-03-6
    • ~95%
    • In-stock
      Ethyl thiophene-2-carboxylate|CS-W016234
      2810-04-0

    References

    • Lee, Jong Chan; Choi, Youngsup Synthetic Communications, 1998 , vol. 28, # 11 p. 2021 - 2026

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   1.9248
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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