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CS-W001157 4
Total: USD 88.00

(R,R)-MeMe-Box

  • CAS No. 280755-86-4

  • Cat. No. CS-0145111
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R,R)-MeMe-Box|CS-0145111

Structure of 280755-86-4

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General Information

  • CAS No. 280755-86-4
  • Cat. No. CS-0145111
  • Purity ≥96%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₈N₂O₂
  • Molecular Weight 210.27
  • Synonym(s) Oxazole, 2,2'-(1-methylethylidene)bis[4,5-dihydro-4-methyl-, (4R,4'R)- (9CI)
  • SMILES C[C@@H]1COC(C(C)(C)C2=N[C@H](C)CO2)=N1

Description

(R,R)-MeMe-Box is a bench-stable, chiral auxiliary featuring two methyl-substituted box ligand frameworks. This configuration enables stereoselective transformations in asymmetric synthesis, offering predictable stereocontrol and enhanced reaction efficiency under standard conditions.

Application

(R,R)-MeMe-Box serves as a highly effective chiral ligand in asymmetric catalysis, enabling enantioselective transformations such as allylic alkylation and conjugate addition. Its rigid, electron-rich structure enhances stereocontrol and catalyst stability, while the methyl-substituted box framework improves solubility and operational robustness. Widely employed in transition-metal-catalyzed reactions, it facilitates high enantiomeric excesses under mild conditions, making it a practical choice for scalable synthesis of chiral building blocks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   1.647
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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