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CS-W001157 4
Total: USD 88.00

1-(4-Chlorophenyl)cyclobutanecarbonitrile

  • CAS No. 28049-61-8

  • Cat. No. CS-W010718
  • Purity≥95%
  • MDL No.MFCD00065239

*For research and further manufacturing use only, not for direct human use.

1-(4-Chlorophenyl)cyclobutanecarbonitrile|CS-W010718

Structure of 28049-61-8

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General Information

  • CAS No. 28049-61-8
  • Cat. No. CS-W010718
  • Purity ≥95%
  • MDL No. MFCD00065239
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀ClN
  • Molecular Weight 191.66
  • Synonym(s) 1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile
  • SMILES ClC1=CC=C(C=C1)C1(CCC1)C#N

Description

1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile is also referred as 1-(4-chlorophenyl)-1-cyanocyclobutane.1-(4-Chlorophenyl)-1-cyclobutanecarbonitrile (1-(4-chlorophenyl)-1-cyanocyclobutane) can be used in the synthesis of pharmacologically active metabolites of the anti-obesity drug-sibutramine.

Synthesis

  • Route1

    References

    • REVIVA PHARMAMEUTICALS, INC. Patent: WO2008/34142 A2, 2008 ; Location in patent: Page/Page column 43-44 ;
  • Route2

    References

    • The Boots Company plc Patent: US4522828 A1, 1985 ;
  • Route3
    • null|null
      352-33-0
    • null|null
      4426-11-3
    • ~87%
    • In-stock
      1-(4-Chlorophenyl)cyclobutanecarbonitrile|CS-W010718
      28049-61-8

    References

    • Krishnamurthy, Dhileepkumar; Han, Zhengxu; Wald, Stephen A.; Senanayake, Chris H. Tetrahedron Letters, 2002 , vol. 43, # 13 p. 2331 - 2333

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312+H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   23.79
  • LogP   3.28528
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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