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CS-W001157 4
Total: USD 88.00

3-Amino-2,6-dimethoxypyridine

  • CAS No. 28020-37-3

  • Cat. No. CS-W005692
  • Purity≥95%
  • MDL No.MFCD00832865

*For research and further manufacturing use only, not for direct human use.

3-Amino-2,6-dimethoxypyridine|CS-W005692

Structure of 28020-37-3

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General Information

  • CAS No. 28020-37-3
  • Cat. No. CS-W005692
  • Purity ≥95%
  • MDL No. MFCD00832865
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂O₂
  • Molecular Weight 154.17
  • Synonym(s) 2,6-Dimethoxypyridine-3-amine
  • SMILES NC1=CC=C(N=C1OC)OC

Description

3-Amino-2,6-dimethoxypyridine features a pyridine core functionalized with amino and methoxy groups at electron-rich positions, enabling robust coupling in cross-coupling reactions. The ortho-methoxy substituents enhance solubility and stabilize reactive intermediates under standard conditions. This compound serves as a key building block for bioactive heterocycles in medicinal chemistry and agrochemical development.

Application

3-Amino-2,6-dimethoxypyridine serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridine scaffolds via palladium-catalyzed cross-coupling and electrophilic substitution reactions. The amino group facilitates derivatization, while the ortho-dimethoxy arrangement provides enhanced stability and favorable electronic properties for heterocycle construction. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for iterative synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   57.37
  • LogP   0.681
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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