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CS-W001157 4
Total: USD 88.00

(S)-1-(Thiophen-2-yl)ethan-1-amine

  • CAS No. 27948-34-1

  • Cat. No. CS-0106541
  • Purity≥95%
  • MDL No.MFCD09822151

*For research and further manufacturing use only, not for direct human use.

(S)-1-(Thiophen-2-yl)ethan-1-amine|CS-0106541

Structure of 27948-34-1

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General Information

  • CAS No. 27948-34-1
  • Cat. No. CS-0106541
  • Purity ≥95%
  • MDL No. MFCD09822151
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉NS
  • Molecular Weight 127.21
  • Synonym(s) (S)-1-(Thiophen-2-yl)ethanamine
  • SMILES N[C@@H](C)C1=CC=CS1

Description

(S)-1-(Thiophen-2-yl)ethan-1-amine is a chiral amine featuring a thiophene ring directly linked to a stereogenic center. This configuration imparts distinct electronic and steric properties, enabling selective incorporation into asymmetric synthesis. The molecule exhibits enhanced solubility in common organic solvents and stability under standard bench conditions, making it a reliable building block for pharmaceutical intermediates and ligand design.

Application

(S)-1-(Thiophen-2-yl)ethan-1-amine serves as a chiral building block for medicinal chemistry and asymmetric synthesis, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. Its bench-stable, enantiomerically pure form facilitates efficient coupling reactions and functional group manipulations, with proven utility in Pd-catalyzed cross-couplings and amine derivatization.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.7678
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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