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CS-W001157 4
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Benzyl (2-(methylamino)ethyl)carbamate hydrochloride

  • CAS No. 277328-34-4

  • Cat. No. CS-0099846
  • Molecule weight244.72
  • Purity≥98%
  • MDL No.MFCD11112222

*For research and further manufacturing use only, not for direct human use.

Benzyl (2-(methylamino)ethyl)carbamate hydrochloride|CS-0099846

Structure of 277328-34-4

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General Information

  • CAS No. 277328-34-4
  • Cat. No. CS-0099846
  • Purity ≥98%
  • MDL No. MFCD11112222
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇ClN₂O₂
  • Molecular Weight 244.72
  • Synonym(s) 1-CBZ-AMINO-2-METHYLAMINO-ETHANE-HCl
  • SMILES O=C(OCC1=CC=CC=C1)NCCNC.[H]Cl

Description

Benzyl (2-(methylamino)ethyl)carbamate hydrochloride features a bifunctional carbamate linkage and a tertiary amine, enabling efficient conjugation in bioconjugation workflows. The hydrochloride salt enhances solubility and stability under standard conditions, facilitating use in peptide synthesis and medicinal chemistry applications.

Application

Benzyl (2-(methylamino)ethyl)carbamate hydrochloride serves as a stable, bench-ready aminoalkylating agent and protecting group precursor in peptide synthesis and medicinal chemistry. Its hydrochloride salt enhances solubility and handling, enabling efficient reductive amination and amine coupling reactions. The benzyl carbamate moiety provides orthogonal protection for primary amines, facilitating selective functionalization in complex molecule assembly.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.554
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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