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CS-W001157 4
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(3-(Dimethylamino)propyl)triphenylphosphonium bromide hydrobromide

  • CAS No. 27710-82-3

  • Cat. No. CS-0151289
  • Purity≥97%
  • MDL No.MFCD00077740

*For research and further manufacturing use only, not for direct human use.

(3-(Dimethylamino)propyl)triphenylphosphonium bromide hydrobromide|CS-0151289

Structure of 27710-82-3

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General Information

  • CAS No. 27710-82-3
  • Cat. No. CS-0151289
  • Purity ≥97%
  • MDL No. MFCD00077740
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₈Br₂NP
  • Molecular Weight 509.26
  • Synonym(s) Phosphonium,[3-(dimethylamino)propyl]triphenyl bromide hydrobromide
  • SMILES CN(C)CCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.Br.[Br-]

Description

This phosphonium salt features a dimethylaminopropyl chain tethered to a triphenylphosphonium core, delivering enhanced solubility and reactivity in polar media. The hydrobromide counterion stabilizes the cationic center, enabling efficient use in Wittig-type reactions and phase-transfer catalysis under standard conditions.

Application

(3-(Dimethylamino)propyl)triphenylphosphonium bromide hydrobromide serves as a stable, bench-ready phosphonium salt enabling efficient Wittig-type olefination reactions. Its tertiary amine functionality enhances reactivity in ylide formation while maintaining compatibility with diverse functional groups. The compound facilitates high-yielding alkene synthesis under mild conditions and is well-suited for scale-up due to predictable handling and straightforward purification.

Synthesis

  • Route1
    • (3-Bromopropyl)triphenylphosphonium bromide Olopatadine  Impurity|CS-0228817
      3607-17-8
    • null|null
      124-40-3
    • ~79%
    • In-stock
      (3-(Dimethylamino)propyl)triphenylphosphonium bromide hydrobromide|CS-0151289
      27710-82-3

    References

    • NEKTAR THERAPEUTICS; RIGGS-SAUTHIER, Jennifer; DENG, Bo-Liang; GURSAHANI, Hema Patent: WO2012/79017 A1, 2012 ; Location in patent: Page/Page column 68 ; WO 2012/079017 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   3.24
  • LogP   1.5141
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   7

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