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Structure of 27607-33-6
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Cis-cyclooctane-1,2-diol features a rigid, strained cyclooctane backbone with adjacent hydroxyl groups in a cis configuration. This stereochemistry enhances its solubility in polar solvents and facilitates selective transformations in synthetic applications. The molecule exhibits enhanced reactivity at the diol site due to geometric constraints, enabling efficient use in chiral auxiliary design and metal-catalyzed coupling processes.
Cis-cyclooctane-1,2-diol serves as a valuable synthon in stereoselective synthesis, enabling controlled dihydroxylation pathways and facilitating the construction of complex cyclic architectures. Its cis configuration provides predictable stereochemical outcomes in ring-functionalization reactions, while its bench-stable nature supports straightforward handling and purification. The molecule functions effectively in oxidation-sensitive transformations and serves as a key intermediate for accessing bioactive heterocyclic scaffolds through selective deprotection or cyclization protocols.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H303-H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: