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CS-W001157 4
Total: USD 88.00

(1-tert-butoxycarbonylazetidin-3-yl)boronic acid

  • CAS No. 2750139-24-1

  • Cat. No. CS-0858718
  • Molecule weight201.03
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1-tert-butoxycarbonylazetidin-3-yl)boronic acid|CS-0858718

Structure of 2750139-24-1

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General Information

  • CAS No. 2750139-24-1
  • Cat. No. CS-0858718
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆BNO₄
  • Molecular Weight 201.03
  • Synonym(s) None
  • SMILES CC(C)(C)OC(=O)N1CC(B(O)O)C1

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The tert-butoxycarbonyl-protected azetidinyl scaffold offers enhanced stability and selective reactivity in synthetic sequences involving strained heterocycles.

Application

(1-tert-butoxycarbonylazetidin-3-yl)boronic acid serves as a stable, bench-accessible building block for the synthesis of azetidine-containing pharmaceuticals. Its boronic acid functionality enables efficient Suzuki-Miyaura cross-coupling reactions under mild conditions, while the Boc group provides orthogonal protection and facilitates purification. The molecule exhibits good functional group tolerance and is compatible with standard peptide coupling and heterocycle-forming protocols, making it a practical reagent for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   70
  • LogP   0.0801
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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