Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Mpa(Trt)

  • CAS No. 27144-18-9

  • Cat. No. CS-W011872
  • Purity≥98%
  • MDL No.MFCD00237291

*For research and further manufacturing use only, not for direct human use.

Mpa(Trt)|CS-W011872

Structure of 27144-18-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 27144-18-9
  • Cat. No. CS-W011872
  • Purity ≥98%
  • MDL No. MFCD00237291
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₀O₂S
  • Molecular Weight 348.47
  • Synonym(s) None
  • SMILES O=C(O)CCSC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Description

Mpa(Trt) features a trifluoromethylated pyridine moiety that enhances electron deficiency and stability under standard conditions. This scaffold integrates readily into cross-coupling reactions, enabling efficient access to functionalized heterocycles with improved solubility and resistance to hydrolysis in synthetic workflows.

Application

Mpa(Trt) serves as a robust, bench-stable amino protecting group for peptide synthesis and complex molecule assembly. It facilitates efficient coupling reactions with excellent functional group tolerance and enables straightforward deprotection under mild acidic conditions. Its compatibility with diverse synthetic workflows makes it a practical choice for constructing peptide-like scaffolds and heterocyclic systems in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      76-83-5
    • null|null
      107-96-0
    • ~95%
    • In-stock
      Mpa(Trt)|CS-W011872
      27144-18-9

    References

    • Contino-Pepin, Christiane; Parat, Audrey; Patinote, Cindy; Roscoe, Wendi A.; Karlik, Stephen J.; Pucci, Bernard ChemMedChem, 2010 , vol. 5, # 12 p. 2057 - 2064
  • Route2
    • Triphenylmethanol Fimasartan Impurity|CS-0228989
      76-84-6
    • null|null
      107-96-0
    • ~88%
    • In-stock
      Mpa(Trt)|CS-W011872
      27144-18-9

    References

    • Mazzier; Mba; Zerbetto; Moretto Chemical Communications, 2014 , vol. 50, # 35 p. 4571 - 4574
  • Route3
    • null|null
      590-92-1
    • In-stock
      Triphenylmethanethiol|CS-0132389
      3695-77-0
    • ~82%
    • In-stock
      Mpa(Trt)|CS-W011872
      27144-18-9

    References

    • Gazal, Sharon; Gelerman, Garry; Ziv, Ofer; Karpov, Olga; Litman, Pninit; Bracha, Moshe; Afargan, Michel; Gilon, Chaim Journal of Medicinal Chemistry, 2002 , vol. 45, # 8 p. 1665 - 1671

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H413
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   5.1864
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   7

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Mpa(Trt) sigmaMpa(Trt) manufacturerMpa(Trt) priceMpa(Trt) structureMpa(Trt) SDSbuy Mpa(Trt)Mpa(Trt) supplierMpa(Trt) usesMpa(Trt) molecular weightprice of Mpa(Trt)Mpa(Trt) chemical name formula of Mpa(Trt)
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label