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CS-W001157 4
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1,2-Benzisoxazole

  • CAS No. 271-95-4

  • Cat. No. CS-0155959
  • Purity≥97%
  • MDL No.MFCD00005852

*For research and further manufacturing use only, not for direct human use.

1,2-Benzisoxazole|CS-0155959

Structure of 271-95-4

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General Information

  • CAS No. 271-95-4
  • Cat. No. CS-0155959
  • Purity ≥97%
  • MDL No. MFCD00005852
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO
  • Molecular Weight 119.12
  • Synonym(s) Indoxazene
  • SMILES C1=CC=C2C(=C1)C=NO2

Description

1,2-Benzisoxazole derivative zonisamide is a novel antiepileptic drug and is effective for the treatment of partial seizures. 1,2-Benzisoxazole is a potential substrates of rabbit liver aldehyde oxidase.

Synthesis

  • Route1

    References

    • Kalkhambkar, Rajesh G.; Yuvaraj Synthetic Communications, 2014 , vol. 44, # 4 p. 547 - 555
  • Route2
    • (E)-2-Hydroxybenzaldehyde oxime|CS-0309097
      21013-96-7
    • ~64%
    • In-stock
      1,2-Benzisoxazole|CS-0155959
      271-95-4

    References

    • MEMORY PHARMACEUTICALS CORPORATION Patent: US2008/200471 A1, 2008 ; Location in patent: Page/Page column 51 ; US 20080200471 A1
  • Route3
    • In-stock
      tert-Butyl 4-(iodomethyl)piperidine-1-carboxylate|CS-0041008
      145508-94-7
    • ~0%
    • In-stock
      1,2-Benzisoxazole|CS-0155959
      271-95-4
    • null|null
      145509-12-2

    References

    • Pfizer Inc. Patent: US5538984 A1, 1996 ; US 5538984 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.03
  • LogP   1.8278
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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