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CS-W001157 4
Total: USD 88.00

2-(Pyridin-2-yl)ethanamine

  • CAS No. 2706-56-1

  • Cat. No. CS-W005000
  • Purity≥95%
  • MDL No.MFCD00006367

*For research and further manufacturing use only, not for direct human use.

2-(Pyridin-2-yl)ethanamine|CS-W005000

Structure of 2706-56-1

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General Information

  • CAS No. 2706-56-1
  • Cat. No. CS-W005000
  • Purity ≥95%
  • MDL No. MFCD00006367
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀N₂
  • Molecular Weight 122.17
  • Synonym(s) N-ethylpyridin-2-amine
  • SMILES C1=C(CCN)N=CC=C1

Description

2-(Pyridin-2-yl)ethanamine features a pyridine ring linked to an ethylamine side chain, enabling versatile coordination in transition metal catalysis. This amine moiety offers strong basicity and nucleophilicity, facilitating efficient ligand integration in asymmetric synthesis. The compound exhibits good solubility in organic solvents and stability under standard bench conditions.

Application

2-(Pyridin-2-yl)ethanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through its dual functionality. The amine group facilitates straightforward derivatization, while the pyridine ring provides a robust hydrogen-bonding site and metabolic stability. This compound exhibits excellent bench stability and compatibility with standard coupling reactions, making it ideal for modular synthesis workflows.

Synthesis

  • Route1
    • null|null
      100-69-6
    • ~29%
    • In-stock
      2-(Pyridin-2-yl)ethanamine|CS-W005000
      2706-56-1

    References

    • Journal of Organic Chemistry, , vol. 77, # 20 p. 8968 - 8979,12
  • Route2
    • null|null
      100-69-6
    • ~30%
    • In-stock
      2-(Pyridin-2-yl)ethanamine|CS-W005000
      2706-56-1
    • null|null
      15496-36-3

    References

    • Tetrahedron, , vol. 63, # 13 p. 2882 - 2887
  • Route3
    • 2-Amino-1-(pyridin-2-yl)ethan-1-one|CS-0466349
      75140-33-9
    • ~%
    • In-stock
      2-(Pyridin-2-yl)ethanamine|CS-W005000
      2706-56-1

    References

    • Journal of the American Chemical Society, , vol. 67, p. 1468,1469

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.5828
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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