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CS-W001157 4
Total: USD 88.00

Bis(triphenylphosphino)(2-methylphenyl)chloronickel(II)

  • CAS No. 27057-09-6

  • Cat. No. CS-0110820
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Bis(triphenylphosphino)(2-methylphenyl)chloronickel(II)|CS-0110820

Structure of 27057-09-6

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General Information

  • CAS No. 27057-09-6
  • Cat. No. CS-0110820
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₃H₃₇ClNiP₂
  • Molecular Weight 709.85
  • Synonym(s) Chloro(2-methylphenyl)bis(triphenylphosphine)nickel(II)
  • SMILES Cl[Ni]([P](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)([P](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)C7=C(C)C=CC=C7

Application

Bis(triphenylphosphino)(2-methylphenyl)chloronickel(II) serves as a well-defined, bench-stable precatalyst for cross-coupling reactions, enabling efficient C–C and C–heteroatom bond formation under mild conditions. Its ortho-methyl-substituted aryl ligand enhances stability and modulates reactivity, while the phosphine coordination facilitates oxidative addition and transmetalation steps. The complex demonstrates broad functional group tolerance and is particularly effective in Suzuki-Miyaura and Negishi coupling protocols, offering reliable performance in synthetic workflows requiring reproducible catalytic activity and straightforward handling.

Safety Information

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GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H317-H350
Precautionary Statements : P280-P302+P352

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Computational Chemistry Data

  • TPSA   0
  • LogP   8.21082
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   9

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