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CS-W001157 4
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Fmoc-(S)-3-Amino-4-(4-methyl-phenyl)-butyric acid

  • CAS No. 270062-97-0

  • Cat. No. CS-0061297
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Fmoc-(S)-3-Amino-4-(4-methyl-phenyl)-butyric acid|CS-0061297

Structure of 270062-97-0

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General Information

  • CAS No. 270062-97-0
  • Cat. No. CS-0061297
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₅NO₄
  • Molecular Weight 415.48
  • Synonym(s) (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(p-tolyl)butanoic acid
  • SMILES CC1=CC=C(C[C@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)CC(O)=O)C=C1

Description

Fmoc-(S)-3-Amino-4-(4-methyl-phenyl)-butyric acid integrates a para-methylphenyl group and a sterically hindered amino acid backbone, enabling efficient incorporation into peptide chains. This bench-stable building block delivers enhanced solubility and compatibility in solid-phase synthesis workflows.

Application

Fmoc-(S)-3-Amino-4-(4-methylphenyl)butyric acid serves as a versatile building block for the synthesis of peptidomimetics and bioactive scaffolds. The Fmoc group enables efficient solid-phase peptide synthesis, while the pendant para-tolyl group imparts steric and electronic modulation. Its amino and carboxylic acid functionalities facilitate standard coupling reactions, and the molecule exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthetic workflows in medicinal chemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.91952
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   7

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