2'-Amino-2'-deoxyuridine

Name: 2'-Amino-2'-deoxyuridine
Brand: ChemScene
Availability: InStock
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CAS No. 26889-39-4
Cat. No. CS-W014134
Purity≥97%
MDL No.MFCD01317284

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 26889-39-4

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Description

2'-Amino-2'-deoxyuridine features a nucleoside scaffold with a 2'-amino group enhancing solubility and enabling site-specific conjugation. This modification improves binding affinity in oligonucleotide therapeutics and supports efficient incorporation during solid-phase synthesis. The compound exhibits bench-stable handling characteristics and serves as a key building block for functionalized DNA analogs.

Application

2'-Amino-2'-deoxyuridine serves as a valuable nucleoside building block for the synthesis of modified oligonucleotides and antiviral agents. Its 2'-amino functionality enables site-specific conjugation and facilitates incorporation into DNA duplexes with enhanced hybridization affinity. The compound exhibits good bench stability and compatibility with standard phosphoramidite coupling protocols, making it a practical choice for solid-phase synthesis in medicinal chemistry and molecular biology applications.

General Information

CAS No. 26889-39-4
Cat. No. CS-W014134
Purity ≥97%
MDL No. MFCD01317284
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₃N₃O₅
Molecular Weight 243.22
Synonym(s) 2'-NH2-dU
SMILES O=C(NC(C=C1)=O)N1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2N

Computational Chemistry Data

TPSA 130.57
LogP -2.8855
H_Acceptors 7
H_Donors 4
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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2'-Amino-2'-deoxyuridine

CAS No. 26889-39-4

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