Lot numbers can be found on the outside label of a product:
2'-Amino-2'-deoxyuridine
-
CAS No. 26889-39-4
- Cat. No. CS-W014134
- Purity≥97%
- MDL No.MFCD01317284
*For research and further manufacturing use only, not for direct human use.
Structure of 26889-39-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 26889-39-4
- Cat. No. CS-W014134
- Purity ≥97%
- MDL No. MFCD01317284
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₃N₃O₅
- Molecular Weight 243.22
- Synonym(s) 2'-NH2-dU
- SMILES O=C(NC(C=C1)=O)N1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2N
Description
2'-Amino-2'-deoxyuridine features a nucleoside scaffold with a 2'-amino group enhancing solubility and enabling site-specific conjugation. This modification improves binding affinity in oligonucleotide therapeutics and supports efficient incorporation during solid-phase synthesis. The compound exhibits bench-stable handling characteristics and serves as a key building block for functionalized DNA analogs.
Application
2'-Amino-2'-deoxyuridine serves as a valuable nucleoside building block for the synthesis of modified oligonucleotides and antiviral agents. Its 2'-amino functionality enables site-specific conjugation and facilitates incorporation into DNA duplexes with enhanced hybridization affinity. The compound exhibits good bench stability and compatibility with standard phosphoramidite coupling protocols, making it a practical choice for solid-phase synthesis in medicinal chemistry and molecular biology applications.
Synthesis
-
Route1
-
In-stock
26929-65-7 - ~92%
-
In-stock
26889-39-4
References
-
Li, Heting; Jiang, Zhiqin; Wang, Xin; Zheng, Chao Synthetic Communications, 2006 , vol. 36, # 14 p. 1933 - 1940
-
-
Route2
-
725727-88-8 - ~99%
-
In-stock
26889-39-4
References
-
Dai, Qing; Piccirilli, Joseph A. Organic Letters, 2004 , vol. 6, # 13 p. 2169 - 2172
-
-
Route3
-
174221-82-0
- ~86%
-
In-stock
26889-39-4
References
-
McGee; Sebesta; O'Rourke; Martinez; Jung; Pieken Tetrahedron Letters, 1996 , vol. 37, # 12 p. 1995 - 1998
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 130.57
- LogP -2.8855
- H_Acceptors 7
- H_Donors 4
- Rotatable_Bonds 2
Similar Products
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2'-Amino-2'-deoxyuridine sigma2'-Amino-2'-deoxyuridine manufacturer2'-Amino-2'-deoxyuridine price2'-Amino-2'-deoxyuridine structure2'-Amino-2'-deoxyuridine SDSbuy 2'-Amino-2'-deoxyuridine2'-Amino-2'-deoxyuridine supplier2'-Amino-2'-deoxyuridine uses2'-Amino-2'-deoxyuridine molecular weightprice of 2'-Amino-2'-deoxyuridine2'-Amino-2'-deoxyuridine chemical name formula of 2'-Amino-2'-deoxyuridine