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CS-W001157 4
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5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine;dihydrochloride

  • CAS No. 2682114-27-6

  • Cat. No. CS-0879629
  • Molecule weight210.10
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine;dihydrochloride|CS-0879629

Structure of 2682114-27-6

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General Information

  • CAS No. 2682114-27-6
  • Cat. No. CS-0879629
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃Cl₂N₃
  • Molecular Weight 210.10
  • Synonym(s) None
  • SMILES Cl.Cl.C1NCC2N(CC1)N=CC=2

Description

This dihydrochloride salt of 5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine offers enhanced solubility and stability for synthetic applications. The protonated heterocyclic core facilitates efficient coupling reactions in medicinal chemistry workflows. Bench-stable and moisture-tolerant, it serves as a key scaffold for bioactive compound development.

Application

5,6,7,8-Tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine; dihydrochloride serves as a versatile heterocyclic scaffold for medicinal chemistry applications, enabling efficient construction of fused bicyclic systems. The dihydrochloride salt enhances solubility and stability in aqueous and protic media, facilitating straightforward handling and purification. It functions as a key building block in the synthesis of kinase inhibitors and CNS-targeted compounds, offering robust compatibility with standard coupling and functionalization protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   1.22
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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