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Structure of 2682-32-8
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N-Methylpropiolamide features a conjugated alkyne amide structure that enables efficient incorporation into click chemistry workflows. The methyl group enhances solubility and metabolic stability, while the terminal alkyne supports copper-catalyzed azide-alkyne cycloaddition. This reagent combines synthetic versatility with bench-stable handling for bioconjugation and materials applications.
N-Methylpropiolamide serves as a versatile building block in synthetic organic chemistry, enabling efficient access to α,β-unsaturated amides and heterocyclic scaffolds. Its conjugated alkyne functionality facilitates reliable copper-catalyzed cycloadditions and nucleophilic additions, while the N-methyl group enhances stability and solubility. The compound exhibits excellent bench stability and compatibility with common functional groups, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: