7-Chloro-3,4-dihydronaphthalen-1(2H)-one

Name: 7-Chloro-3,4-dihydronaphthalen-1(2H)-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 26673-32-5
Cat. No. CS-W002865
Purity≥98%
MDL No.MFCD01928386

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

7-Chloro-3,4-dihydronaphthalen-1(2H)-one|CS-W002865

Structure of 26673-32-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 26673-32-5
Cat. No. CS-W002865
Purity ≥98%
MDL No. MFCD01928386
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₉ClO
Molecular Weight 180.63
Synonym(s) 7-Chloro-3,4-dihydro-1(2H)-naphthalenone
SMILES Clc1ccc2c(c1)C(=O)CCC2

Description

7-Chloro-3,4-dihydronaphthalen-1(2H)-one is a chlorinated dihydronaphthalenone scaffold featuring a labile enolizable carbonyl and electron-deficient aromatic ring. This structure integrates readily into synthetic routes requiring π-electron modulation, offering enhanced reactivity in electrophilic substitution and transition-metal-catalyzed coupling processes under standard conditions.

Application

7-Chloro-3,4-dihydronaphthalen-1(2H)-one serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and drug-like scaffolds. Its fused bicyclic structure provides defined stereochemistry and enhanced metabolic stability, while the ketone functionality facilitates nucleophilic additions and enolate chemistry. Bench-stable and compatible with standard functional group transformations, it functions effectively in multistep syntheses for API development.

Synthesis

Route1
- In-stock
  
  22009-40-1
- ~%
- In-stock
  
  26673-32-5
References
- AstraZeneca AB Patent: US6265397 B1, 2001 ; US 6265397 B1
Route2
- In-stock
  
  4619-18-5
- ~82%
- In-stock
  
  26673-32-5
References
- Carroll, F. Ivy; Blough, Bruce E.; Abraham, Philip; Mills, Andrew C.; Holleman, J. Ashley; Wolckenhauer, Scott A.; Decker, Ann M.; Landavazo, Antonio; McElroy, K. Timothy; Navarro, Hernan A.; Gatch, Michael B.; Forster, Michael J. Journal of Medicinal Chemistry, 2009 , vol. 52, # 21 p. 6768 - 6781
Route3
- In-stock
  
  4619-18-5
- ~%
- In-stock
  
  26673-32-5
- In-stock
  
  529-34-0
References
- Zeneca Limited Patent: US5502048 A1, 1996 ; US 5502048 A

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 17.07
LogP 2.859
H_Acceptors 1
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Ketone

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

7-Chloro-3,4-dihydronaphthalen-1(2H)-one sigma7-Chloro-3,4-dihydronaphthalen-1(2H)-one manufacturer7-Chloro-3,4-dihydronaphthalen-1(2H)-one price7-Chloro-3,4-dihydronaphthalen-1(2H)-one structure7-Chloro-3,4-dihydronaphthalen-1(2H)-one SDSbuy 7-Chloro-3,4-dihydronaphthalen-1(2H)-one7-Chloro-3,4-dihydronaphthalen-1(2H)-one supplier7-Chloro-3,4-dihydronaphthalen-1(2H)-one uses7-Chloro-3,4-dihydronaphthalen-1(2H)-one molecular weightprice of 7-Chloro-3,4-dihydronaphthalen-1(2H)-one7-Chloro-3,4-dihydronaphthalen-1(2H)-one chemical name formula of 7-Chloro-3,4-dihydronaphthalen-1(2H)-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

7-Chloro-3,4-dihydronaphthalen-1(2H)-one

CAS No. 26673-32-5

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words