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CS-W001157 4
Total: USD 88.00

3-Bromodibenzo[b,d]furan

  • CAS No. 26608-06-0

  • Cat. No. CS-D0380
  • Purity≥98%
  • MDL No.MFCD09966042

*For research and further manufacturing use only, not for direct human use.

3-Bromodibenzo[b,d]furan|CS-D0380

Structure of 26608-06-0

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General Information

  • CAS No. 26608-06-0
  • Cat. No. CS-D0380
  • Purity ≥98%
  • MDL No. MFCD09966042
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₇BrO
  • Molecular Weight 247.09
  • Synonym(s) None
  • SMILES BrC1=CC=C2C(OC3=CC=CC=C23)=C1

Description

3-Bromodibenzo[b,d]furan is a brominated polycyclic aromatic compound featuring a dibenzo[b,d]furan core with a reactive bromine substituent at the 3-position. This halogenated scaffold enables efficient cross-coupling transformations, serving as a key intermediate in the synthesis of complex heterocyclic systems and functional materials. The molecule exhibits enhanced stability under standard reaction conditions and demonstrates compatibility with palladium-catalyzed coupling protocols.

Application

3-Bromodibenzo[b,d]furan serves as a versatile building block in the synthesis of polycyclic aromatic systems and heterocyclic scaffolds. The bromine substituent enables palladium-catalyzed cross-coupling reactions, facilitating efficient C–C bond formation under mild conditions. Its stability, crystalline nature, and compatibility with diverse functional groups make it well-suited for applications in medicinal chemistry and materials science.

Synthesis

  • Route1
    • null|null
      1285719-49-4
    • ~60%
    • In-stock
      3-Bromodibenzo[b,d]furan|CS-D0380
      26608-06-0

    References

    • Idemitsu Kosan Co., Ltd. Patent: EP2484665 A1, 2012 ; Location in patent: Page/Page column 66 ;
  • Route2
    • null|null
      861605-94-9
    • ~81%
    • In-stock
      3-Bromodibenzo[b,d]furan|CS-D0380
      26608-06-0

    References

    • Maetani, Shinji; Fukuyama, Takahide; Ryu, Ilhyong Organic Letters, 2013 , vol. 15, # 11 p. 2754 - 2757
  • Route3
    • 4'-Bromo-[1,1'-biphenyl]-2-ol|CS-0163051
      21849-89-8
    • ~39%
    • In-stock
      3-Bromodibenzo[b,d]furan|CS-D0380
      26608-06-0

    References

    • Wei, Ye; Yoshikai, Naohiko Organic Letters, 2011 , vol. 13, # 20 p. 5504 - 5507

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   13.14
  • LogP   4.3485
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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