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CS-W001157 4
Total: USD 88.00

3-(4-Aminophenoxy)aniline

  • CAS No. 2657-87-6

  • Cat. No. CS-W015613
  • Purity≥97%
  • MDL No.MFCD00036097

*For research and further manufacturing use only, not for direct human use.

3-(4-Aminophenoxy)aniline|CS-W015613

Structure of 2657-87-6

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General Information

  • CAS No. 2657-87-6
  • Cat. No. CS-W015613
  • Purity ≥97%
  • MDL No. MFCD00036097
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂N₂O
  • Molecular Weight 200.24
  • Synonym(s) 4-(3-AMINO-PHENOXY)-PHENYLAMINE
  • SMILES NC1=CC=CC(OC2=CC=C(C=C2)N)=C1

Description

3-(4-Aminophenoxy)aniline features a dual amine architecture bridging two aromatic rings, enabling robust conjugation in molecular architectures. This electron-rich scaffold integrates readily into functional materials and pharmaceutical intermediates under standard conditions, offering enhanced solubility and stability during synthesis.

Application

3-(4-Aminophenoxy)aniline serves as a versatile building block for the synthesis of functionalized aromatic systems, enabling efficient access to complex scaffolds through standard coupling and cyclization reactions. Its dual amine and ether functionalities provide orthogonal reactivity for sequential modifications, while its bench-stable nature facilitates handling and purification in multi-step syntheses.

Synthesis

  • Route1
    • null|null
      591-27-5
    • In-stock
      4-Iodoaniline, 98%|CS-W008946
      540-37-4
    • ~54%
    • In-stock
      3-(4-Aminophenoxy)aniline|CS-W015613
      2657-87-6

    References

    • Maiti, Debabrata; Buchwald, Stephen L. Journal of the American Chemical Society, 2009 , vol. 131, # 47 p. 17423 - 17429
  • Route2

    References

    • Brewster; Strain Journal of the American Chemical Society, 1934 , vol. 56, p. 117,118
  • Route3
    • null|null
      1124-31-8
    • ~%
    • In-stock
      3-(4-Aminophenoxy)aniline|CS-W015613
      2657-87-6

    References

    • Brewster; Strain Journal of the American Chemical Society, 1934 , vol. 56, p. 117,118

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08,GHS09
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅱ
Hazard Statements : H301+H311+H331-H317-H341-H351-H361-H410
Precautionary Statements : P261-P264-P270-P271-P272-P273-P280-P302+P352-P304+P340-P330-P361+P364-P362+P364-P391-P405-P501

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Computational Chemistry Data

  • TPSA   61.27
  • LogP   2.6433
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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