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CS-W001157 4
Total: USD 88.00

5-Cyclopentyl-1H-pyrazol-3-amine

  • CAS No. 264209-16-7

  • Cat. No. CS-0050502
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Cyclopentyl-1H-pyrazol-3-amine|CS-0050502

Structure of 264209-16-7

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General Information

  • CAS No. 264209-16-7
  • Cat. No. CS-0050502
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₃N₃
  • Molecular Weight 151.21
  • Synonym(s) 3-Cyclopentyl-1H-pyrazol-5-amine
  • SMILES NC1=NNC(=C1)C1CCCC1

Description

5-Cyclopentyl-1H-pyrazol-3-amine features a bicyclic pyrazole core with a cyclopentyl substituent at the 5-position and a primary amine at the 3-position. This scaffold integrates a sterically accessible nitrogen donor with enhanced lipophilicity, enabling efficient incorporation into bioactive molecules for medicinal chemistry campaigns.

Application

5-Cyclopentyl-1H-pyrazol-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its stability under routine synthetic conditions and compatibility with diverse reaction partners facilitate efficient access to pyrazole-based scaffolds relevant to drug discovery programs.

Synthesis

  • Route1

    References

    • ASTRAZENECA AB Patent: US2008/4302 A1, 2008 ; Location in patent: Page/Page column 52-53 ; US 20080004302 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   54.7
  • LogP   1.6495
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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