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CS-W001157 4
Total: USD 88.00

(S)-3-Bromo-2-(1-methoxyethyl)pyridine

  • CAS No. 2641451-44-5

  • Cat. No. CS-0312114
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-3-Bromo-2-(1-methoxyethyl)pyridine|CS-0312114

Structure of 2641451-44-5

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General Information

  • CAS No. 2641451-44-5
  • Cat. No. CS-0312114
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrNO
  • Molecular Weight 216.08
  • Synonym(s) None
  • SMILES C[C@@H](C1=NC=CC=C1Br)OC

Description

This chiral pyridine derivative features a stereodefined bromide at the 3-position and a methoxyethyl side chain at the 2-position, enabling precise coupling in asymmetric synthesis. The bench-stable, moisture-tolerant structure facilitates efficient transition metal-catalyzed transformations and serves as a key scaffold for bioactive molecule construction.

Application

(S)-3-Bromo-2-(1-methoxyethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined stereochemistry and stable bromopyridine functionality. The methoxyethyl side chain offers moderate steric bulk and enhanced solubility, facilitating purification and downstream derivatization. This compound functions effectively in Suzuki-Miyaura and Negishi coupling protocols, providing access to complex pyridyl scaffolds relevant to pharmaceutical development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.5515
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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