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Structure of 2639204-09-2
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8-Methoxyisoquinoline-6-carboxylic acid features a fused bicyclic core with strategic functionalization: a methoxy group at the 8-position enhances solubility and modulates electron density, while the C6-carboxylic acid enables direct coupling or salt formation. This combination delivers robust stability under standard bench conditions and facilitates integration into bioactive scaffolds for medicinal chemistry applications.
8-Methoxyisoquinoline-6-carboxylic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling direct access to isoquinoline-based scaffolds prevalent in bioactive molecules. Its carboxylic acid functionality facilitates amide coupling, esterification, and metal-catalyzed transformations, while the methoxy group provides moderate electron donation and orthogonal reactivity. The molecule exhibits bench stability, ease of purification, and compatibility with standard synthetic workflows, making it well-suited for lead optimization campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: