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CS-W001157 4
Total: USD 88.00

H-Ser-OEt.HCl

  • CAS No. 26348-61-8

  • Cat. No. CS-W017712
  • Purity≥98%
  • MDL No.MFCD00012594

*For research and further manufacturing use only, not for direct human use.

H-Ser-OEt.HCl|CS-W017712

Structure of 26348-61-8

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General Information

  • CAS No. 26348-61-8
  • Cat. No. CS-W017712
  • Purity ≥98%
  • MDL No. MFCD00012594
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO₃
  • Molecular Weight 169.61
  • Synonym(s) None
  • SMILES N[C@@H](CO)C(OCC)=O.Cl

Description

H-Ser-OEt·HCl is a bench-stable, moisture-tolerant amino acid derivative featuring a protected hydroxyl group and a protonated amine. This form simplifies handling in peptide synthesis workflows, enabling direct incorporation into chain elongation sequences without additional deprotection steps. The ethyl ester facilitates efficient coupling reactions under standard conditions.

Application

H-Ser-OEt·HCl serves as a stable, bench-ready building block for peptide synthesis and medicinal chemistry campaigns. The ethyl ester functionality enables straightforward incorporation into peptide chains via standard coupling protocols, while the protonated amine ensures solubility and ease of handling. Its well-documented compatibility with common protecting group strategies facilitates efficient access to serine-containing sequences and heterocyclic scaffolds in drug discovery workflows.

Synthesis

  • Route1
    • null|null
      64-17-5
    • In-stock
      H-Ser-OH Amino acid impurity|CS-1733142
      56-45-1
    • ~95%
    • In-stock
      H-Ser-OEt.HCl|CS-W017712
      26348-61-8

    References

    • van Dijk, Maarten; Postma, Tobias M.; Rijkers, Dirk T.S.; Liskamp, Rob M.J.; van Nostrum, Cornelus F.; Hennink, Wim E. Polymer, 2010 , vol. 51, # 12 p. 2479 - 2485
  • Route2
    • null|null
      81852-20-2
    • ~81%
    • In-stock
      H-Ser-OEt.HCl|CS-W017712
      26348-61-8

    References

    • Field, Steven J.; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 591 - 594
  • Route3
    • null|null
      3914-13-4
    • ~%
    • In-stock
      H-Ser-OEt.HCl|CS-W017712
      26348-61-8

    References

    • Field, Steven J.; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 591 - 594

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.55
  • LogP   -0.7091
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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