Oxetan-3-yl 4-methylbenzene-1-sulfonate

Name: Oxetan-3-yl 4-methylbenzene-1-sulfonate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 26272-83-3
Cat. No. CS-0037430
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Oxetan-3-yl 4-methylbenzene-1-sulfonate|CS-0037430

Structure of 26272-83-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 26272-83-3
Cat. No. CS-0037430
Purity ≥98%
MDL No. None
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₂O₄S
Molecular Weight 228.27
Synonym(s) p-Toluenesulfonic Acid 3-Oxetanyl Ester
SMILES CC1=CC=C(C=C1)S(=O)(=O)OC2COC2

Description

Oxetan-3-yl 4-methylbenzene-1-sulfonate is a bench-stable, moisture-tolerant oxetane derivative that enables efficient C–C bond formation via ring-opening reactions. The electron-deficient oxetane integrates readily into complex molecular architectures, while the p-tolylsulfonyl group ensures excellent leaving-group ability. This reagent streamlines late-stage functionalization in synthetic and medicinal chemistry workflows.

Application

Oxetan-3-yl 4-methylbenzene-1-sulfonate serves as a stable, bench-friendly oxetane electrophile that facilitates efficient C–O bond formation in nucleophilic substitution reactions. Its sulfonate leaving group enables reliable coupling with amines, alcohols, and thiols under mild conditions, making it a practical reagent for constructing oxetane-containing scaffolds in medicinal chemistry and process development.

Synthesis

Route1
- In-stock
  
  7748-36-9
- 98-59-9
- ~93%
- In-stock
  
  26272-83-3
References
- MERCK SHARP and DOHME CORP.; WU, Wen-Lian; BURNETT, Duane, A.; GREENLEE, William, J. Patent: WO2012/138678 A1, 2012 ; Location in patent: Page/Page column 33 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 52.6
LogP 1.09912
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 3

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Oxetane compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Material Science Polymer/Macromolecule Reagents Monomers Oxetane Monomers

Key Words

Oxetan-3-yl 4-methylbenzene-1-sulfonate sigmaOxetan-3-yl 4-methylbenzene-1-sulfonate manufacturerOxetan-3-yl 4-methylbenzene-1-sulfonate priceOxetan-3-yl 4-methylbenzene-1-sulfonate structureOxetan-3-yl 4-methylbenzene-1-sulfonate SDSbuy Oxetan-3-yl 4-methylbenzene-1-sulfonateOxetan-3-yl 4-methylbenzene-1-sulfonate supplierOxetan-3-yl 4-methylbenzene-1-sulfonate usesOxetan-3-yl 4-methylbenzene-1-sulfonate molecular weightprice of Oxetan-3-yl 4-methylbenzene-1-sulfonateOxetan-3-yl 4-methylbenzene-1-sulfonate chemical name formula of Oxetan-3-yl 4-methylbenzene-1-sulfonate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Oxetan-3-yl 4-methylbenzene-1-sulfonate

CAS No. 26272-83-3

Recommended Products