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CS-W001157 4
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(S)-3-(2-Bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid

  • CAS No. 261165-02-0

  • Cat. No. CS-W009287
  • Purity≥98%
  • MDL No.MFCD01317709

*For research and further manufacturing use only, not for direct human use.

(S)-3-(2-Bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid|CS-W009287

Structure of 261165-02-0

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General Information

  • CAS No. 261165-02-0
  • Cat. No. CS-W009287
  • Purity ≥98%
  • MDL No. MFCD01317709
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈BrNO₄
  • Molecular Weight 344.20
  • Synonym(s) Boc-Phe(2-Br)-OH
  • SMILES O=C(O)[C@H](CC1=CC=CC=C1Br)NC(OC(C)(C)C)=O

Description

This chiral building block features a (S)-configured stereocenter flanked by a brominated aromatic ring and a Boc-protected amino group. The structure enables direct incorporation into peptide backbones or conjugation workflows, offering stability under standard bench conditions and compatibility with diverse synthetic transformations.

Application

(S)-3-(2-Bromophenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid serves as a valuable chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry and peptide-based drug discovery. The molecule combines a readily functionalized aryl bromide with a stable Boc-protected amino acid moiety, enabling subsequent cross-coupling reactions and orthogonal deprotection strategies. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient access to complex scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.9695
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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