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CS-W001157 4
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Benzyl (E)-prop-1-en-1-ylcarbamate

  • CAS No. 260967-14-4

  • Cat. No. CS-0108790
  • Purity≥98%
  • MDL No.MFCD30183516

*For research and further manufacturing use only, not for direct human use.

Benzyl (E)-prop-1-en-1-ylcarbamate|CS-0108790

Structure of 260967-14-4

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General Information

  • CAS No. 260967-14-4
  • Cat. No. CS-0108790
  • Purity ≥98%
  • MDL No. MFCD30183516
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₃NO₂
  • Molecular Weight 191.23
  • Synonym(s) (E)-benzyl prop-1-en-1-ylcarbamate
  • SMILES O=C(OCC1=CC=CC=C1)N/C=C/C

Description

Benzyl (E)-prop-1-en-1-ylcarbamate features a stereodefined (E)-alkene moiety paired with a labile carbamate group, enabling selective deprotection under mild conditions. This bifunctional scaffold integrates seamlessly into synthetic sequences requiring orthogonal protection strategies. The benzyl ester component enhances solubility and facilitates purification.

Application

Benzyl (E)-prop-1-en-1-ylcarbamate serves as a stable, bench-friendly carbamate protecting group for amines, enabling selective deprotection under mild conditions. It functions effectively in multistep syntheses involving sensitive intermediates, with compatibility across diverse reaction types including hydrogenation and electrophilic functionalization. Its orthogonal stability to common protecting groups facilitates strategic synthesis planning in medicinal chemistry and API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   2.4464
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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