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Structure of 260267-07-0
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5,6-Difluoro-1H-indole-3-carbaldehyde features a fluorinated indole core with electron-withdrawing difluoromethyl substituents at the 5- and 6-positions, enhancing electrophilicity at the carbonyl carbon. This bench-stable aldehyde integrates readily into transition-metal-catalyzed couplings and serves as a key building block for bioactive heterocycles in medicinal chemistry and agrochemical research.
5,6-Difluoro-1H-indole-3-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocyclic scaffolds. Its electrophilic aldehyde group facilitates standard coupling reactions, while the ortho-fluorine substituents enhance metabolic stability and modulate electronic properties. The compound exhibits bench stability and compatibility with common protecting group strategies, facilitating efficient downstream functionalization in API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: