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Structure of 259269-84-6
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2-Amino-3-bromo-5-fluorobenzoic acid features a strategically positioned amino group flanked by bromo and fluoro substituents, enabling selective functionalization in pharmaceutical intermediates. This electron-deficient aromatic system supports efficient coupling reactions under standard conditions, while the carboxylic acid moiety facilitates direct conjugation or derivatization. The molecule exhibits bench-stable handling characteristics and compatibility with diverse reaction environments.
2-Amino-3-bromo-5-fluorobenzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted aryl scaffold enables efficient palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates derivatization via amide formation or esterification. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative medicinal chemistry campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: