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CS-W001157 4
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(2S,4R)-4-((tert-Butyldiphenylsilyl)oxy)pyrrolidine-2-carboxylic acid

  • CAS No. 259212-61-8

  • Cat. No. CS-0046868
  • Molecule weight369.53
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2S,4R)-4-((tert-Butyldiphenylsilyl)oxy)pyrrolidine-2-carboxylic acid|CS-0046868

Structure of 259212-61-8

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General Information

  • CAS No. 259212-61-8
  • Cat. No. CS-0046868
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₇NO₃Si
  • Molecular Weight 369.53
  • Synonym(s) trans-4-(tert-Butyldiphenylsilyloxy)-L-proline
  • SMILES O=C([C@H]1NC[C@H](O[Si](C2=CC=CC=C2)(C(C)(C)C)C3=CC=CC=C3)C1)O

Synthesis

  • Route1
    • null|null
      866327-29-9
    • ~98%
    • In-stock
      (2S,4R)-4-((tert-Butyldiphenylsilyl)oxy)pyrrolidine-2-carboxylic acid|CS-0046868
      259212-61-8

    References

    • Freund, Matthias H.; Tsogoeva, Svetlana B. Synlett, 2011 , # 4 p. 503 - 507
  • Route2
    • null|null
      58479-61-1
    • In-stock
      L-Hydroxyproline|CS-W008928
      51-35-4
    • ~98%
    • In-stock
      (2S,4R)-4-((tert-Butyldiphenylsilyl)oxy)pyrrolidine-2-carboxylic acid|CS-0046868
      259212-61-8

    References

    • Delaney, Joshua P.; Brozinski, Hannah L.; Henderson, Luke C. Organic and Biomolecular Chemistry, 2013 , vol. 11, # 18 p. 2951 - 2960
  • Route3

    References

    • Organic Letters, , vol. 7, # 19 p. 4185 - 4188

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   2.3781
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   5

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