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CS-W001157 4
Total: USD 88.00

2,5-Dimercaptoterephthalic acid

  • CAS No. 25906-66-5

  • Cat. No. CS-0110742
  • Molecule weight230.25
  • Purity≥95%
  • MDL No.MFCD23160366

*For research and further manufacturing use only, not for direct human use.

2,5-Dimercaptoterephthalic acid|CS-0110742

Structure of 25906-66-5

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General Information

  • CAS No. 25906-66-5
  • Cat. No. CS-0110742
  • Purity ≥95%
  • MDL No. MFCD23160366
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆O₄S₂
  • Molecular Weight 230.25
  • Synonym(s) 2,5-Disulfhydrylbenzene-1,4-dicarboxylic acid
  • SMILES O=C(O)C1=CC(S)=C(C=C1S)C(=O)O

Description

2,5-Dimercaptoterephthalic acid features two thiol groups positioned at para-adjacent sites on a terephthalate backbone, enabling robust metal chelation and coordination. This bifunctional architecture supports integration into metal-organic frameworks and surface functionalization protocols. The molecule exhibits enhanced stability in aqueous environments and facilitates efficient conjugation with gold nanoparticles and transition metals.

Application

2,5-Dimercaptoterephthalic acid serves as a versatile bifunctional building block for metal-organic frameworks and thiol-based conjugation chemistries. Its ortho-dithiol functionality enables robust coordination with transition metals and selective bioconjugation under mild conditions. The molecule exhibits excellent bench stability, facilitates straightforward purification via recrystallization, and functions reliably in standard coupling protocols for heterocyclic scaffold construction and surface functionalization.

Synthesis

  • Route1
    • null|null
      25906-67-6
    • ~97%
    • In-stock
      2,5-Dimercaptoterephthalic acid|CS-0110742
      25906-66-5

    References

    • Vial, Laurent; Ludlow, R. Frederick; Leclaire, Julien; Perez-Fernandez, Ruth; Otto, Sijbren Journal of the American Chemical Society, 2006 , vol. 128, # 31 p. 10253 - 10257
  • Route2

    References

    • Vial, Laurent; Ludlow, R. Frederick; Leclaire, Julien; Perez-Fernandez, Ruth; Otto, Sijbren Journal of the American Chemical Society, 2006 , vol. 128, # 31 p. 10253 - 10257
  • Route3
    • null|null
      25906-63-2
    • ~%
    • In-stock
      2,5-Dimercaptoterephthalic acid|CS-0110742
      25906-66-5

    References

    • Vial, Laurent; Ludlow, R. Frederick; Leclaire, Julien; Perez-Fernandez, Ruth; Otto, Sijbren Journal of the American Chemical Society, 2006 , vol. 128, # 31 p. 10253 - 10257

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

Quality Control

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   1.6604
  • H_Acceptors   4
  • H_Donors   4
  • Rotatable_Bonds   2

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