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Structure of 258506-74-0
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4-Chloro-6-iodopyrimidine is a halogenated pyrimidine scaffold enabling selective cross-coupling reactions. The ortho-halogen arrangement facilitates sequential functionalization, while the electron-deficient ring enhances reactivity in palladium-catalyzed transformations. This compound serves as a key intermediate for pharmaceutical and agrochemical development.
4-Chloro-6-iodopyrimidine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The chlorine and iodine substituents allow sequential functionalization under orthogonal conditions, facilitating the construction of complex pyrimidine-based scaffolds. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for iterative synthesis of pharmaceutical intermediates and heterocyclic libraries.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: