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CS-W001157 4
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tert-Butyl 4-cyano-4-(4-fluorophenyl)piperidine-1-carboxylate

  • CAS No. 256951-79-8

  • Cat. No. CS-0133026
  • Molecule weight304.36
  • Purity≥95%
  • MDL No.MFCD09788613

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-cyano-4-(4-fluorophenyl)piperidine-1-carboxylate|CS-0133026

Structure of 256951-79-8

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General Information

  • CAS No. 256951-79-8
  • Cat. No. CS-0133026
  • Purity ≥95%
  • MDL No. MFCD09788613
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₂₁FN₂O₂
  • Molecular Weight 304.36
  • Synonym(s) 1-Piperidinecarboxylic acid, 4-cyano-4-(4-fluorophenyl)-, 1,1-dimethylethyl ester
  • SMILES O=C(N1CCC(C2=CC=C(F)C=C2)(C#N)CC1)OC(C)(C)C

Synthesis

  • Route1

    References

    • SCHERING CORPORATION Patent: WO2004/4722 A1, 2004 ; Location in patent: Page/Page column 20; 50-51 ; WO 2004/004722 A1
  • Route2

    References

    • ASTRAZENECA AB Patent: WO2004/56771 A1, 2004 ; Location in patent: Page 23 ; WO 2004/056771 A1
  • Route3

    References

    • Liu, Jian; Jian, Tianying; Sebhat, Iyassu; Nargund, Ravi Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5115 - 5117

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   53.33
  • LogP   3.61798
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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