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CS-W001157 4
Total: USD 88.00

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

  • CAS No. 256376-62-2

  • Cat. No. CS-0536368
  • Purity≥98%
  • MDL No.MFCD20268233

*For research and further manufacturing use only, not for direct human use.

1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide|CS-0536368

Structure of 256376-62-2

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General Information

  • CAS No. 256376-62-2
  • Cat. No. CS-0536368
  • Purity ≥98%
  • MDL No. MFCD20268233
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₁FN₄O
  • Molecular Weight 270.26
  • Synonym(s) Riociguat-19
  • SMILES C1=CC=C(C(=C1)CN2C3=C(C=CC=N3)C(=N2)C(=O)N)F

Synthesis

  • Route1
    • Ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylate|CS-0464955
      256376-59-7
    • ~99%
    • 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide|CS-0536368
      256376-62-2

    References

    • Straub, Alexander; Stasch, Johannes-Peter; Alonso-Alija, Cristina; Benet-Buchholz, Jordi; Ducke, Bernhard; Feurer, Achim; Fuerstner, Chantal Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 6 p. 781 - 784 Title/Abstract Full Text View citing articles Show Details Straub, Alexander; Benet-Buckholz, Jordi; Froede, Rita; Kern, Armin; Kohlsdorfer, Christian; Schmitt, Peter; Schwarz, Thomas; Siefert, Hans Martin; Stasch, Johannes Peter Bioorganic and medicinal chemistry, 2002 , vol. 10, # 6 p. 1711 - 1717
  • Route2

    References

    • Straub, Alexander; Stasch, Johannes-Peter; Alonso-Alija, Cristina; Benet-Buchholz, Jordi; Ducke, Bernhard; Feurer, Achim; Fuerstner, Chantal Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 6 p. 781 - 784 Title/Abstract Full Text View citing articles Show Details Straub, Alexander; Benet-Buckholz, Jordi; Froede, Rita; Kern, Armin; Kohlsdorfer, Christian; Schmitt, Peter; Schwarz, Thomas; Siefert, Hans Martin; Stasch, Johannes Peter Bioorganic and medicinal chemistry, 2002 , vol. 10, # 6 p. 1711 - 1717
  • Route3

    References

    • Straub, Alexander; Stasch, Johannes-Peter; Alonso-Alija, Cristina; Benet-Buchholz, Jordi; Ducke, Bernhard; Feurer, Achim; Fuerstner, Chantal Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 6 p. 781 - 784 Title/Abstract Full Text View citing articles Show Details Straub, Alexander; Benet-Buckholz, Jordi; Froede, Rita; Kern, Armin; Kohlsdorfer, Christian; Schmitt, Peter; Schwarz, Thomas; Siefert, Hans Martin; Stasch, Johannes Peter Bioorganic and medicinal chemistry, 2002 , vol. 10, # 6 p. 1711 - 1717

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   73.8
  • LogP   1.7176
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   3

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