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Structure of 255864-58-5
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tert-Butyl 2-ethynylpiperidine-1-carboxylate features a reactive alkyne handle integrated into a piperidine scaffold, enabling efficient coupling in transition-metal-catalyzed reactions. The tert-butyl ester group provides stability and ease of removal under mild acidic conditions, while the ethynyl moiety facilitates conjugation with azides or metal complexes. This combination supports rapid access to functionalized heterocycles in medicinal chemistry and materials synthesis.
tert-Butyl 2-ethynylpiperidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted piperidines via copper-catalyzed coupling reactions. The terminal alkyne functionality facilitates reliable Sonogashira and click chemistry transformations, while the tert-butyl carbamate group provides excellent bench stability and convenient deprotection under mild acidic conditions. Its compatibility with diverse functional groups makes it ideal for modular synthesis of bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: