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CS-W001157 4
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2-(Trifluoroacetyl)pyrrole

  • CAS No. 2557-70-2

  • Cat. No. CS-W018807
  • Purity≥98%
  • MDL No.MFCD00141809

*For research and further manufacturing use only, not for direct human use.

2-(Trifluoroacetyl)pyrrole|CS-W018807

Structure of 2557-70-2

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General Information

  • CAS No. 2557-70-2
  • Cat. No. CS-W018807
  • Purity ≥98%
  • MDL No. MFCD00141809
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄F₃NO
  • Molecular Weight 163.10
  • Synonym(s) Ethanone, 2,2,2-trifluoro-1-(1H-pyrrol-2-yl)-
  • SMILES C1=C(C(C(F)(F)F)=O)[NH]C=C1

Description

2-(Trifluoroacetyl)pyrrole features a strongly electron-deficient pyrrole core stabilized by the trifluoroacetyl group, enabling selective reactivity in cross-coupling and cycloaddition processes. This bench-stable compound integrates readily into complex heterocyclic architectures under mild conditions.

Synthesis

  • Route1
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      109-97-7
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      407-25-0
    • ~99%
    • In-stock
      2-(Trifluoroacetyl)pyrrole|CS-W018807
      2557-70-2

    References

    • Grancho; Pereira; Miguel; Rocha, Gonsalves A M; Burrows Photochemistry and photobiology, 2002 , vol. 75, # 3 p. 249 - 256
  • Route2
    • null|null
      109-97-7
    • null|null
      407-25-0
    • ~74%
    • In-stock
      2-(Trifluoroacetyl)pyrrole|CS-W018807
      2557-70-2
    • null|null
      76-05-1

    References

    • Pelaez; Burgos Paci; Argueello Tetrahedron Letters, 2009 , vol. 50, # 17 p. 1934 - 1938
  • Route3
    • In-stock
      2,2,2-Trifluoro-1-(piperidin-1-yl)ethan-1-one|CS-0143336
      340-07-8
    • null|null
      38480-28-3
    • ~%
    • In-stock
      2-(Trifluoroacetyl)pyrrole|CS-W018807
      2557-70-2

    References

    • Angewandte Chemie - International Edition, , vol. 52, # 52 p. 14191 - 14195 Angew. Chem., , vol. 125, # 52 p. 14441 - 14445,5

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   32.86
  • LogP   1.7597
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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