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CS-W001157 4
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Benzyltriethoxysilane

  • CAS No. 2549-99-7

  • Cat. No. CS-0151946
  • Purity≥95%
  • MDL No.MFCD00026751

*For research and further manufacturing use only, not for direct human use.

Benzyltriethoxysilane|CS-0151946

Structure of 2549-99-7

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General Information

  • CAS No. 2549-99-7
  • Cat. No. CS-0151946
  • Purity ≥95%
  • MDL No. MFCD00026751
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₂O₃Si
  • Molecular Weight 254.40
  • Synonym(s) Benzene, ((triethoxysilyl)methyl)-
  • SMILES CCO[Si](CC1=CC=CC=C1)(OCC)OCC

Description

Benzyltriethoxysilane serves as a versatile organosilicon reagent for surface functionalization and sol-gel processing. This moisture-tolerant compound features a benzyl group that integrates into hybrid organic-inorganic networks, enhancing compatibility with polymer matrices. The ethoxy groups hydrolyze readily under mild conditions, enabling covalent anchoring to oxide surfaces.

Application

Benzyltriethoxysilane serves as a reliable silyl protecting group for alcohols and amines, offering excellent bench stability and compatibility with standard deprotection protocols. It facilitates efficient Si–O bond formation under mild conditions and enables orthogonal protection in complex molecule synthesis. The triethoxysilyl moiety provides high reactivity in Staudinger-type coupling reactions and supports robust functional group tolerance across diverse synthetic sequences.

Synthesis

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      Benzyltriethoxysilane|CS-0151946
      2549-99-7

    References

    • Journal of the Chemical Society, , vol. 95, p. 302 - 314 Ber. Dtsch. Chem. Ges., , vol. 41, p. 3390 - 3395 Si: MVol.C, 75, page 209 - 211
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      Benzyltriethoxysilane|CS-0151946
      2549-99-7
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      18782-68-8

    References

    • Journal of the Chemical Society, , vol. 95, p. 302 - 314 Si: MVol.C, 94, page 257 - 259
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      Benzyltriethoxysilane|CS-0151946
      2549-99-7

    References

    • Journal of the Chemical Society, , vol. 95, p. 313 Chemische Berichte, , vol. 41, p. 3393

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   2.8167
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   8

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