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Structure of 25458-45-1
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1-Bromo-4-(methoxymethoxy)benzene features a bromine atom and a methoxymethoxy group positioned para to each other on the benzene ring. This configuration enables selective cross-coupling reactions under standard conditions, while the ether functionality enhances solubility in common organic solvents. The molecule exhibits bench-stable handling characteristics and integrates readily into complex synthetic sequences.
1-Bromo-4-(methoxymethoxy)benzene serves as a versatile aryl halide building block for Suzuki and Stille coupling reactions, offering excellent functional group tolerance and bench stability. The methoxymethoxy group provides reliable protection of phenolic hydroxyls under standard conditions, enabling orthogonal deprotection strategies in complex molecule synthesis. Its compatibility with palladium-catalyzed transformations makes it a practical choice for constructing biaryl scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: