Tyrosinase-IN-22

Name: Tyrosinase-IN-22
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 25369-78-2
Cat. No. CS-0094540
Purity≥97%
MDL No.MFCD01044385

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 25369-78-2

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Description

Tyrosinase-IN-22 is a potent, selective inhibitor of tyrosinase, designed for research in pigmentation pathways and enzymatic kinetics. This compound features a stable scaffold with high binding affinity, enabling effective modulation of enzyme activity under physiological conditions. Its optimized pharmacophore enhances cellular penetration and target engagement, making it suitable for in vitro studies and mechanistic investigations.

Application

Tyrosinase-IN-22 serves as a potent, selective inhibitor of tyrosinase, enabling targeted modulation of melanin biosynthesis. Its pyrazole-based scaffold exhibits robust bench stability and favorable solubility, facilitating straightforward integration into in vitro enzymatic assays. Functions effectively in standard kinetic inhibition studies and supports structure-activity investigations within pigmentation research, offering reliable performance for medicinal chemistry screening campaigns.

General Information

CAS No. 25369-78-2
Cat. No. CS-0094540
Purity ≥97%
MDL No. MFCD01044385
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅ClN₂S
Molecular Weight 184.65
Synonym(s) 5-Chloro-2-mercaptobenzimidazole
SMILES S=C1NC2=CC(Cl)=CC=C2N1

Computational Chemistry Data

TPSA 31.58
LogP 2.87889
H_Acceptors 1
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Benzimidazole compounds

Key Words

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Tyrosinase-IN-22

CAS No. 25369-78-2

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