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Structure of 253168-94-4
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This ethanamine derivative features a 3-ethoxy-4-methoxyphenyl group linked to a methylsulfonyl-bearing carbon, delivering enhanced solubility and metabolic stability. The para-methoxy substitution improves electron density, while the sulfonamide moiety enables strong hydrogen bonding. Designed for medicinal chemistry applications, it integrates readily into bioactive scaffolds requiring polar, stable side chains under standard conditions.
1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine serves as a versatile building block for medicinal chemistry campaigns, enabling efficient access to bioactive scaffolds via amide coupling and reductive amination. The molecule features a phenolic ether motif with orthogonal functional handles—namely the primary amine and methylsulfonyl group—enabling selective derivatization under mild conditions. Bench-stable and readily purified by standard chromatography, it supports scalable synthesis of kinase inhibitors and CNS-targeted compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: