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Ethyl 3-amino-1H-pyrrole-2-carboxylate hydrochloride

  • CAS No. 252932-49-3

  • Cat. No. CS-D1578
  • Purity≥97%
  • MDL No.MFCD04038917

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-amino-1H-pyrrole-2-carboxylate hydrochloride|CS-D1578

Structure of 252932-49-3

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General Information

  • CAS No. 252932-49-3
  • Cat. No. CS-D1578
  • Purity ≥97%
  • MDL No. MFCD04038917
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁ClN₂O₂
  • Molecular Weight 190.63
  • Synonym(s) 3-Amino-1H-pyrrole-2-carboxylic acid ethyl ester hydrochloride; 3-Amino-2-ethoxycarbonylpyrrole hydrochloride; 3-amino-2-ethoxycarbonylpyrrole.hydrochloride
  • SMILES O=C(C1=C(N)C=CN1)OCC.[H]Cl

Description

Ethyl 3-amino-1H-pyrrole-2-carboxylate hydrochloride delivers a bench-stable, moisture-tolerant pyrrole scaffold bearing a pendant amino group and ester functionality. This dual-functionalized intermediate enables direct incorporation into diverse heterocyclic architectures, facilitating efficient access to complex pyrrole-based frameworks in medicinal chemistry and materials synthesis.

Application

Ethyl 3-amino-1H-pyrrole-2-carboxylate hydrochloride serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyrroles and heterocyclic scaffolds. The amino group facilitates nucleophilic substitution and coupling reactions, while the ester functionality supports derivatization via hydrolysis or reduction. Bench-stable and readily purified, it functions effectively in standard peptide-like coupling protocols and is compatible with diverse functional groups encountered in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   68.11
  • LogP   1.1954
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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