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CS-W001157 4
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N3-PEG3-CH2CH2-Boc

  • CAS No. 252881-73-5

  • Cat. No. CS-0022130
  • Purity≥98%
  • MDL No.MFCD22201543

*For research and further manufacturing use only, not for direct human use.

N3-PEG3-CH2CH2-Boc|CS-0022130

Structure of 252881-73-5

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General Information

  • CAS No. 252881-73-5
  • Cat. No. CS-0022130
  • Purity ≥98%
  • MDL No. MFCD22201543
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₅N₃O₅
  • Molecular Weight 303.35
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCN=[N+]=[N-]

Description

N3-PEG3-CH2CH2-Boc features a triazole-linked PEG3 spacer flanked by a reactive azide and a stable Boc-protected amine. This bifunctional reagent enables site-specific conjugation in bioorthogonal workflows, offering enhanced solubility and stability under physiological conditions.

Application

N3-PEG3-CH2CH2-Boc serves as a versatile bifunctional building block for conjugation and protection strategies in synthetic chemistry. The azide group enables reliable copper-catalyzed or strain-promoted cycloaddition reactions, while the Boc-protected amine offers orthogonal functionality for subsequent deprotection and functionalization. Its PEG3 spacer provides enhanced solubility and reduced aggregation, facilitating efficient purification and handling in peptide and small-molecule synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   102.75
  • LogP   2.0783
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   12

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