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Potassium (4-acetylphenyl)trifluoroborate

  • CAS No. 252726-24-2

  • Cat. No. CS-0323860
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Potassium (4-acetylphenyl)trifluoroborate|CS-0323860

Structure of 252726-24-2

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General Information

  • CAS No. 252726-24-2
  • Cat. No. CS-0323860
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BF₃KO
  • Molecular Weight 226.05
  • Synonym(s) Potassium 4-acetylphenyltrifluoroborate
  • SMILES CC(=O)C1=CC=C(C=C1)[B-](F)(F)F.[K+]

Description

Potassium (4-acetylphenyl)trifluoroborate delivers a bench-stable, moisture-tolerant boronate handle that integrates seamlessly into Suzuki-Miyaura cross-coupling reactions. The para-acetyl group enhances reactivity and enables downstream functionalization, while the trifluoroborate moiety ensures high stability and ease of handling under standard conditions.

Application

Potassium (4-acetylphenyl)trifluoroborate serves as a stable, bench-ready boronate building block for palladium-catalyzed cross-coupling reactions. It facilitates efficient Suzuki-Miyaura coupling with aryl halides and triflates, enabling rapid access to biaryl scaffolds common in pharmaceutical and agrochemical research. The acetyl group provides orthogonal functionality for further derivatization, while the trifluoroborate moiety ensures excellent stability, ease of handling, and compatibility with diverse reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   -1.0524
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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