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CS-W001157 4
Total: USD 88.00

4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylic acid

  • CAS No. 252720-31-3

  • Cat. No. CS-0001951
  • Purity≥95%
  • MDL No.MFCD03790944

*For research and further manufacturing use only, not for direct human use.

4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylic acid|CS-0001951

Structure of 252720-31-3

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General Information

  • CAS No. 252720-31-3
  • Cat. No. CS-0001951
  • Purity ≥95%
  • MDL No. MFCD03790944
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀N₂O₄
  • Molecular Weight 244.29
  • Synonym(s) N-BOC-AMINO-PIPERIDINYL-1,1-CARBOXYLIC ACID
  • SMILES O=C(OC(C)(C)C)NC1(CCNCC1)C(O)=O

Description

This piperidine derivative features a tert-butoxycarbonyl-protected amine and a carboxylic acid group, enabling direct incorporation into peptide synthesis. The protected amine allows selective functionalization, while the carboxylic acid facilitates conjugation or derivatization under standard coupling conditions.

Application

4-((tert-Butoxycarbonyl)amino)piperidine-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of piperidine-based scaffolds prevalent in bioactive molecules. The protected amine and carboxylic acid functionalities offer orthogonal reactivity, facilitating peptide coupling and selective deprotection under mild acidic conditions. Bench-stable and readily purified by standard chromatographic methods, it functions efficiently in multi-step syntheses requiring precise functional group management.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   87.66
  • LogP   0.7179
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   2

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